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Ketamine belongs to a class of drugs known as dissociative anesthetics. It is also known as Ketalar, Ketanest, and Ketaset.
Other drugs in this category include the hallucinogen, phencyclidine (PCP), dextromethorphan (DXM), and nitrous oxide, or laughing gas.
These types of drugs can make a person feel detached from sensations and surroundings, as if they are floating outside their body.
Therapeutic uses of ketamine powder
Ketamine is most often used in veterinary medicine. In humans, it can induce and maintain general anesthesia before, during, and after surgery.
For medical purposes, ketamine is either injected into a muscle or given through an intravenous (IV) line.
It is considered safe as an anesthetic, because it does not reduce blood pressure or lower the breathing rate.
The fact that it does not need an electricity supply, oxygen, or highly trained staff makes it a suitable option in less wealthy countries and in disaster zones.
In human medical practice, it is used in procedures such as:
- cardiac catheterization
- skin grafts
- orthopedic procedures
- diagnostic procedures on the eye, ear, nose, and throat
- minor surgical interventions, such as dental extractions
It has been used in a hospital setting to control seizures in patients with status epilepticus (SE), a type of epilepsy that can lead to brain damage and death. However, researchers point out that ketamine is normally used for this purpose after 5 to 6 other options have proven ineffective.
It is also an analgesic, and, in lower doses, it can relieve pain.
Researchers are looking into other possible medical uses of ketamine, particularly in the areas of treatment-resistant depression, suicide prevention, and substance use disorders. However, this use is controversial.
Researchers for the American Psychological Association (APA) noted in April 2017 that a number of doctors prescribe ketamine “off-label,” for people with treatment-resistant depression.
However, they caution:
In a study published in BMC Medical Ethics, researchers urge doctors to “minimize the risk to patients” by considering carefully the evidence before prescribing ketamine off-label for patients to treat depression and prevent suicide.
Citing “questionable practice” regarding the prescription of ketamine, they point out that there is not enough evidence to prove that ketamine is safe, and that some studies supporting its use have not been sufficiently rigorous in terms of research ethics.
They call for open debate, more research, and for doctors to try all other options first, before prescribing ketamine.
The National Institutes of Health (NIH) are currently supporting research into whether ketamine may help people with treatment-resistant depression.
Ketamine Powder Side Effect
Ketamine use can have a wide variety of adverse effects, including:
- changes in perceptions of color or sound
- hallucinations, confusion, and delirium
- dissociation from body or identity
- difficulty thinking or learning
- dilated pupils and changes in eyesight
- inability to control eye movements
- involuntary muscle movements and muscle stiffness
- slurred speech
- slow heart beat
- behavioral changes
- increased pressure in the eyes and brain
When used as an anesthetic in humans, doctors combine it with another drug to prevent hallucinations.
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